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ARTICLE
Year : 1999  |  Volume : 11  |  Issue : 2  |  Page : 40-46

The possible role of L-form bacteria in periapical disease


1 Chief, Endodontics section and Director of the Endodontic, Residency Program, Veterans Administration, Medical Center, Long Beach, California and Professor of Endodontics, Loma Linda University, School of Dentistry, Loma Linda, California, USA
2 Former Endodontic Resident, Veterans Administration Medical Center, Long Beach, Currently in private practice limited to Endodontics, Fresno, California, USA
3 Professor and acting Chairman, Department of Endodontics, The Hebrew University-Hadassah Faculty of Dental Medicine, Jerusalem, Israel
4 Endodontic Resident, Veterans Administration Medical Center, Long Beach, California, USA

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Source of Support: None, Conflict of Interest: None


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Bacteria can undergo morphological transition after exposure to certain agents such as penicillin. Such bacteria, known as L-form bacteria have a demaged cell wall and are pleomorphic. They can remain dormant in a periapical lesion for months or years after a successful endodontic treatment, and can then start replication. Such phenomenon may be responsible for acute exacerbation of chronic apical lesion. This study attempts to define the role of L-form bacteria in periapical disease.


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